diff --git a/src/src/IO/DICOM/DICOMDirectoryHelper.cpp b/src/src/IO/DICOM/DICOMDirectoryHelper.cpp
index 455e5cf..558c738 100644
--- a/src/src/IO/DICOM/DICOMDirectoryHelper.cpp
+++ b/src/src/IO/DICOM/DICOMDirectoryHelper.cpp
@@ -258,26 +258,9 @@ void DICOMDirectoryHelper::readImageProperty(ExtendMedicalImageProperties* prope
         dataset->findAndGetFloat64(DcmTagKey(0x0020, 0x0032), position[1], 1);
         dataset->findAndGetFloat64(DcmTagKey(0x0020, 0x0032), position[2], 2);
         property->SetPosition(position);
+        // get orientation transform matrix and MToW WToM transform matrix
+        property->ComputeTransformMatrix();
     }
-    double *d = property->GetDirectionCosine();
-    double xVector[3] = {d[0], d[1], d[2]};
-    double yVector[3] = {d[3], d[4], d[5]};
-    double zVector[3] = {0, 0, 0};
-    vtkMath::Cross(xVector, yVector, zVector);
-    auto  matrix = property->GetModelToWorldMatrix();
-    matrix->Identity();
-    matrix->SetElement( 0,0, xVector[0]);
-    matrix->SetElement( 1,0, xVector[1]);
-    matrix->SetElement( 2,0, xVector[2]);
-    matrix->SetElement( 0,1, yVector[0]);
-    matrix->SetElement( 1,1, yVector[1]);
-    matrix->SetElement( 2,1, yVector[2]);
-    matrix->SetElement( 0,2, zVector[0]);
-    matrix->SetElement( 1,2, zVector[1]);
-    matrix->SetElement( 2,2, zVector[2]);
-
-    vtkMatrix4x4::Invert(matrix, property->GetWorldToModelMatrix() );
-    matrix = property->GetWorldToModelMatrix();
 
     if (files.size()>1){
         DcmFileFormat file2;
diff --git a/src/src/IO/DICOM/ExtendMedicalImageProperties.cpp b/src/src/IO/DICOM/ExtendMedicalImageProperties.cpp
index 0805c90..631e7a4 100644
--- a/src/src/IO/DICOM/ExtendMedicalImageProperties.cpp
+++ b/src/src/IO/DICOM/ExtendMedicalImageProperties.cpp
@@ -2,9 +2,12 @@
 // Created by Krad on 2022/2/10.
 //
 
-#include <vtkObjectFactory.h>
 #include "ExtendMedicalImageProperties.h"
 
+#include <vtkObjectFactory.h>
+#include <vtkTransform.h>
+#include <vtkMath.h>
+
 //----------------------------------------------------------------------------
 vtkStandardNewMacro(ExtendMedicalImageProperties)
 
@@ -21,3 +24,33 @@ void ExtendMedicalImageProperties::Clear() {
     this->SetStudyUID(nullptr);
     this->SetSeriesUID(nullptr);
 }
+
+void ExtendMedicalImageProperties::ComputeTransformMatrix() {
+    double *d = GetDirectionCosine();
+    //通过orientation的数值，计算Z轴方向向量，并记录
+    double xVector[3] = {d[0], d[1], d[2]};
+    double yVector[3] = {d[3], d[4], d[5]};
+    vtkMath::Cross(xVector, yVector, ZVector);
+
+    //根据三轴向量构建矩阵
+    OrientationMatrix->Zero();
+    OrientationMatrix->SetElement(0, 0, xVector[0]);
+    OrientationMatrix->SetElement(1, 0, xVector[1]);
+    OrientationMatrix->SetElement(2, 0, xVector[2]);
+    OrientationMatrix->SetElement(0, 1, yVector[0]);
+    OrientationMatrix->SetElement(1, 1, yVector[1]);
+    OrientationMatrix->SetElement(2, 1, yVector[2]);
+    OrientationMatrix->SetElement(0, 2, ZVector[0]);
+    OrientationMatrix->SetElement(1, 2, ZVector[1]);
+    OrientationMatrix->SetElement(2, 2, ZVector[2]);
+    OrientationMatrix->SetElement(3, 3, 1);
+    //计算MToW变换矩阵和逆矩阵WToM
+    vtkNew<vtkTransform> transform;
+    transform->PostMultiply();
+    transform->SetMatrix(OrientationMatrix);
+    transform->Translate(GetPosition());
+    transform->GetMatrix(ModelToWorldMatrix);
+    WorldToModelMatrix->DeepCopy(ModelToWorldMatrix);
+    WorldToModelMatrix->Invert();
+}
+
diff --git a/src/src/IO/DICOM/ExtendMedicalImageProperties.h b/src/src/IO/DICOM/ExtendMedicalImageProperties.h
index 3ab0eb0..c1fabe1 100644
--- a/src/src/IO/DICOM/ExtendMedicalImageProperties.h
+++ b/src/src/IO/DICOM/ExtendMedicalImageProperties.h
@@ -39,6 +39,8 @@ public:
     vtkSetVector3Macro(Position,double);
     vtkGetVector3Macro(Position,double);
 
+    vtkGetVector3Macro(ZVector,double);
+
     const std::vector<std::string>& GetFileNames(){
         return  FileNames;
     }
@@ -74,12 +76,16 @@ public:
     void SetUniqueID(const std::string& id){
         uniqueID = id;
     }
+    vtkMatrix4x4* GetOrientationMatrix(){
+        return OrientationMatrix.Get();
+    }
     vtkMatrix4x4* GetWorldToModelMatrix(){
-        return worldToModelMatrix.Get();
+        return WorldToModelMatrix.Get();
     }
     vtkMatrix4x4* GetModelToWorldMatrix(){
-        return modelToWorldMatrix.Get();
+        return ModelToWorldMatrix.Get();
     }
+    void ComputeTransformMatrix();
 
 protected:
     ExtendMedicalImageProperties();
@@ -88,12 +94,14 @@ protected:
     char * SeriesUID = nullptr;
     double Spacing[3] ={1.0,1.0,1.0};
     double Position[3] ={.0,.0,.0};
+    double ZVector[3] ={.0,.0,.0};
     long AcquisitionNumber = 0;
     unsigned short SamplePerPixel;
     std::vector<std::string> FileNames;
     std::string uniqueID;
-    vtkNew<vtkMatrix4x4> worldToModelMatrix;
-    vtkNew<vtkMatrix4x4> modelToWorldMatrix;
+    vtkNew<vtkMatrix4x4> OrientationMatrix;
+    vtkNew<vtkMatrix4x4> WorldToModelMatrix;
+    vtkNew<vtkMatrix4x4> ModelToWorldMatrix;
 private:
     ExtendMedicalImageProperties(const ExtendMedicalImageProperties&) = delete;
     void operator=(const ExtendMedicalImageProperties&) = delete;